Uso da dexametasona para prevenção da sensibilidade dental pós-clareamento em consultório: Estudo clínico randomizado, triplo cego, placebo-controlado

Abstract

The main adverse effect of dental bleaching is tooth sensitivity (TS). This study aimed to determine the effect of dexamethasone on TS caused by in-office bleaching. A randomized, parallel design, placebo-controlled, triple-blind, clinical trial was selected on 63 health and young adults who received either a placebo (PG) and dexamethasone (DG). The drugs (8mg) were administered 1 hour prior dental bleaching and extra doses of 4 mg were administered every 6 hours for 48 hours. Two office bleaching sessions were conducted in three applications fifteen minutes from HP 35% (Whiteness HP Maxx, FGM, Joinville, SC, Brazil), for both groups in accordance with the manufacturer’s directions. The TS was recorded on two scales: VAS (0-10) and numeric rating scale NRS (0-4), in different time points. The color evaluation were performed before, one week after first and second session of dental bleaching and one month after dental bleaching with a visual shade guide Vitapan Classical (Vita Zahnfabrik, Bad Säckingen, Germany), Vita Bleachedguide 3D-Master (Vita Zahnfabrik), and spectrophotometer Vita Easyshade (Vita Zahnfabrik). Data were analyzed using the suitable statistical tests (α = 0.05). There was no statistically significant difference between groups for the absolute risk of TS (p = 0.894), and not to the intensity of TS (p > 0.05). The intensity of the TS was greater in periods during bleaching and 1 h post-bleaching with reducing the intensity of the TS over time. Dental bleaching was effective in both groups, with no statistically significant difference when the color of the scales was assessed by Vitapan Classical (p > 0.642), Bleachedguide Vita 3D-Master (p > 0.775) and the spectrophotometer Vita Easyshade (p > 0.582). The use of dexamethasone does not reduce the absolute risk or the intensity of TS during the dental office bleaching.